Ligand Based Pharmacophore Identification and Molecular Docking Studies for Grb2 Inhibitors
نویسندگان
چکیده
منابع مشابه
Ligand Based Pharmacophore Identification and Molecular Docking Studies for Grb2 Inhibitors
Grb2 is an adapter protein involved in the signal transduction and cell communication. The Grb2 is responsible for initiation of kinase signaling by Ras activation which leads to the modification in transcription. Ligand based pharmacophore approach was applied to built the suitable pharmacophore model for Grb2. The best pharmacophore model was selected based on the statistical values and then ...
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ژورنال
عنوان ژورنال: Bulletin of the Korean Chemical Society
سال: 2012
ISSN: 0253-2964
DOI: 10.5012/bkcs.2012.33.5.1707